I use a combination of the gummies and the tinctures to help with a variety of things such as TMJ pain, anxiety and as a sleep aid. The gummies taste great and are fast active. I can begin to feel residual effects, mainly just my body calming, around 5 to 10 minutes after eating one. Definitely eat them around a meal as it certainly heightens the effectiveness. Will most certainly be recommending this product to friends and family!